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Customer Spotlight


HarkerBIO is a young, energetic technology partnering company headquartered within the renowned Hautpman-Woodward Medical Research Institute (HWI) in Buffalo, NY.

HarkerBIO activities focus on the determination and use of macromolecular structures to solve research challenges in Pharma and Biotech; the services include a full suite of gene-to-structure activities, advanced molecular biology, protein chemistry, protein design and protein optimization. Some of HarkerBIO's more specialized offerings include crystallization of full-length antibodies and a proprietary technology (dubbed 'Adaptive Surface Alphabet') that can convert poorly crystalline (or entirely non-crystallizeable) proteins into those suitable for iterative ligand soaking, fragment screening etc. HarkerBIO utilizes the highly successful custom robotic screening pipeline at HWI as well as ARI robotics for follow-up and custom screen creation. We use the Crystal Gryphon for setting up assay plates, the Scorpion for designing optimization screens and re-arraying commercial screens into deep well blocks. Both of these instruments have been workhorses for our lab.



Crystal Phoenix

The Phoenix Liquid Handling System sets up sitting drop, microbatch and hanging drop crystallography plates. Fast, accurate and easy to use. For more information, click on a topic below.