Crystal Gryphon LCP
Crystal Gryphon LCP The Crystal Gryphon LCP combines all of the features of the Gryphon LCP and the Crystal Gryphon into the same compact and reliable system. Capable of doing LCP, sponge phase, bicelle, hanging drop, sitting drop, matrix seeding, and micro batch setups.
CRYSTAL GRYPHON LCP OVERVIEW
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Versatile and upgradeable. Add a nano or LCP dispenser at any point in the future.
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Set up seeding experiments, LCP, sponge phase, bicelle, sitting drop, hanging drop and microbatch assays all on one compact system.
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Dispense 96 buffers at once provides reproducible results due to minimal volatile buffer evaporation.
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A 96 LCP plate can be sealed in under 2 minutes; a vapor diffusion plate in under 1 minute.
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One instrument to dispense buffers and protein with best in class precision, accuracy and reliability.
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No costly disposable tips.
The Gryphon is the industry leading family of dispensers designed specifically for protein crystallography. With unsurpassed reliability, performance and speed, the Gryphon is the ideal dispenser for all of your crystallization assays.
96 Syringe Head
This head consists of 96 syringes with a maximum volume of 100 µL for dispensing buffers and additives. Buffers can be aspirated directly from 2 ml blocks. Volumes can be dispensed accurately down to 100 nL with CVs < 5%. Resilient, flexible needles bend and return to shape. An optional 24 channel head is available for optimization assays.
Protein Head
This head has been specifically designed to dispense protein samples. The wide bore nozzles resist clogging, and a precision glass syringe is used for accurate aspirations. A precision pressure system dispenses protein samples at 50 nL < 5% CVs. The non-contact protein dispense head with on-the-fly dispensing provides speed with no cross-contamination.
LCP/Seeding Head
LCP Syringe Dispense Head This head is used for LCP, sponge phase, bicelle, and seeding assays. The syringe has been designed specifically to dispense viscous compounds like LCP and seed stock. The unique design of the syringe and needle allows the user to slide it into position, so the needle is always aligned. LCP can be dispensed at 25 nL with less than 5% CVs.
CRYSTAL GRYPHON
The Crystal Gryphon can set up sitting drop, hanging drop, and microbatch plates with volumes down to 50 nL. The system consists of a 96 channel syringe head for dispensing buffer solutions and a non-contact protein dispenser. The system comes complete with a computer and easy to use drag and drop software. By combining a 96 channel head with a single channel protein dispense head, a 96 well plate can be set up and sealed in less than 1 minute. This assures evaporation will not affect your assays. An optional 24 channel head is available for setting up optimization plates. With the 24 head and the INTELLI-PLATE® 24-4, you can set up 4 optimization assays with each buffer solution.
GRYPHON LCP
ARI first demonstrated the Crystal Gryphon LCP to the Kobilka lab at Stanford as a prototype in 2011. This instrument, still coming out of development, was used to set up membrane protein crystallization screens that produced diffraction quality crystals, and that team purchased our first device.r setting up LCP, sponge phase, bicelle and seeding assays. LCP can be dispensed and mixed with the system.
By combining a 96 channel with a single channel dispense head, a 96 well assay can be dispensed and sealed in less than 90 seconds. This speed, which reduces evaporation, is essential in creating repeatable experiments. A unique LCP dispense syringe snaps into place and self-aligns eliminating the need for constant calibration. The LCP/Seeding dispense head can dispense LCP and bicelles down to 10 nL.
CRYSTAL GRYPHON LCP
The Crystal Gryphon LCP combines all of the features of the Gryphon LCP and the Crystal into the same compact and reliable system. Capable of doing
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LCP
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Matrix seeding
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Hanging drop
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Sitting drop
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Sponge phase
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Bicelle
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Micro batch
SPECIFICATIONS
Specifications 96 Head for buffer solutions:
LCP Dispense Head:
Protein dispense Head:
Dispense specs are CVs < 5%
Base: 20(51)h x 23(59)w x 23(59)d in(cm)
68 lbs, 31 Kg
Wash: 13(33)h x 6.5(17)w x 14(36)d in(cm)
5.5 lbs, 2.5 Kg
Protein head: 9.5(24)h x 6(15)w x 16(41)d in(cm)
18.5 lbs, 8.4 Kg Base: 120/240 Vac, 3 A, 50/60 Hz
Wash: 120/240 Vac, 2 A, 50/60 Hz
Protein head: 120/240 Vac, 1.5 A, 50/60 Hz
Windows 10
50 nL to 100 µL
10 nL to 2 µL
50 nL to 100 µL
ACCESSORIES
LCP Syringe
The LCP syringes for the Gryphon are designed to self-align and easily snap into place on the Gryphon.
620-1005-02 50 uL Syringe
620-1005-03 100 uL Syringe
620-1100-01 ARI Dispense Needle Assy, Short, .250 (3/pk)
620-1100-02 ARI Dispense Needle Assy, Long, .900 (3/pk)
For use with seeding
LCP Coupling and Ferrule
These ferrule are for use with the Gryphon syringes and the LCP Mixer.
The ferrules are shown left to right in the adjacent image. The LCP Mixer and the Gryphon use the same ferrules, but different couplings.
620-1200-01 ARI-ARI Mix Ferrule Assy w/ Coupling
620-1200-02 ARI-Hamilton Mix Ferrule Assy w/ Coupling
620-1200-03 Hamilton-Hamilton Mix Ferrule Assy w/ Coupling
LCP Couplings
These ferrule are for use with the Gryphon syringes and the LCP Mixer.
The ferrules are shown left to right in the adjacent image. The LCP Mixer and the Gryphon use the same ferrules, but different couplings.
620-1200-01 ARI-ARI Mix Ferrule Assy w/ Coupling
620-1200-02 ARI-Hamilton Mix Ferrule Assy w/ Coupling
620-1200-03 Hamilton-Hamilton Mix Ferrule Assy w/ Coupling
LCP Mixing Station
These ferrule are for use with the Gryphon syringes and the LCP Mixer.
The ferrules are shown left to right in the adjacent image. The LCP Mixer and the Gryphon use the same ferrules, but different couplings.
620-1200-01 ARI-ARI Mix Ferrule Assy w/ Coupling
620-1200-02 ARI-Hamilton Mix Ferrule Assy w/ Coupling
620-1200-03 Hamilton-Hamilton Mix Ferrule Assy w/ Coupling
Hanging Drop Seals and Fixture
These ferrule are for use with the Gryphon syringes and the LCP Mixer.
The ferrules are shown left to right in the adjacent image. The LCP Mixer and the Gryphon use the same ferrules, but different couplings.
620-1200-01 ARI-ARI Mix Ferrule Assy w/ Coupling
620-1200-02 ARI-Hamilton Mix Ferrule Assy w/ Coupling
620-1200-03 Hamilton-Hamilton Mix Ferrule Assy w/ Coupling